Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development
نویسندگان
چکیده
منابع مشابه
Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development.
Bcl9 and Bcl9l (Bcl9/9l) encode Wnt signaling components that mediate the interaction between β-catenin and Pygopus (Pygo) via two evolutionarily conserved domains, HD1 and HD2, respectively. We generated mouse strains lacking these domains to probe the β-catenin-dependent and β-catenin-independent roles of Bcl9/9l and Pygo during mouse development. While lens development is critically dependen...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2014
ISSN: 0890-9369,1549-5477
DOI: 10.1101/gad.246140.114